We are a small computational biology research group in the School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, UK. We are interested in the structure, function and evolution of classes of genes whose final products are functional RNA molecules. We spend the majority of our time thinking about microRNAs, a fascinating class of tiny RNA molecules that are involved in the regulation of gene expression, and play roles in essentially all biological processes in animals and plants. The main methods and technologies that we use in our day-to-day work are genome sequence analysis, deep sequencing, transcriptomics, and RNA structure prediction.
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